Clinical Guideline for the Diagnosis of Beryllium Sensitization and Chronic Beryllium Disease
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چکیده
This Guideline provides the clinical diagnostic criteria for beryllium sensitization and chronic beryllium disease (CBD; old term = berylliosis), based on the latest available medical literature and consultation with leading experts in the field. This Guideline does not address exposure prevention, workplace safety, or treatment. In addition, this Guideline is not intended to supplant all adjudicative decisions in cases that meet the case definition and which are crucial to the administration of the Washington workers’ compensation system.
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Beryllium Sensitization Progresses to Chronic Beryllium Disease
The blood beryllium lymphocyte proliferation test is used in medical surveillance to identify both beryllium sensitization and chronic beryllium disease. Approximately 50% of individuals with beryllium sensitization have chronic beryllium disease at the time of their initial clinical evaluation; however, the rate of progression from beryllium sensitization to chronic beryllium disease is unknow...
متن کاملBeryllium sensitization progresses to chronic beryllium disease: a longitudinal study of disease risk.
The blood beryllium lymphocyte proliferation test is used in medical surveillance to identify both beryllium sensitization and chronic beryllium disease. Approximately 50% of individuals with beryllium sensitization have chronic beryllium disease at the time of their initial clinical evaluation; however, the rate of progression from beryllium sensitization to chronic beryllium disease is unknow...
متن کاملSystematic review: Progression of beryllium sensitization to chronic beryllium disease.
BACKGROUND The relevance of beryllium sensitization testing for occupational health practice and prevention is unclear. AIMS To analyse the natural course of beryllium sensitization and clarify the prognosis following cessation of exposure among sensitized workers. METHODS An electronic literature search was conducted in PubMed, Embase, Toxline and Cochrane databases supplemented by a manua...
متن کاملChronic Beryllium Disease and Sensitization at a Beryllium Processing Facility
We conducted a medical screening for beryllium disease of 577 former workers from a beryllium processing facility. The screening included a medical and work history questionnaire, a chest radiograph, and blood lymphocyte proliferation testing for beryllium. A task exposure and a job exposure matrix were constructed to examine the association between exposure to beryllium and the development of ...
متن کاملSensitization and chronic beryllium disease among workers in copper-beryllium distribution centers.
OBJECTIVE Little is known about the risk of sensitization and chronic beryllium disease (CBD) among workers performing limited processing of copper-beryllium alloys downstream of the primary beryllium industry. In this study, we performed a cross-sectional survey of employees at three copper-beryllium alloy distribution centers. METHODS One hundred workers were invited to be tested for beryll...
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